Improving vector control interventions
Centers for Disease Control and Prevention (CDC: OADS BAA 2016-N-17844)
This project will develop a ‘rapid’ approach for the delivery of indoor residual spraying by changing the equipment used and targeting indoor resting locations of Aedes aegypti.
USAID:AID‐OAA‐F‐16‐00094, Gregor Devine, QIMR, Australia, PI)
In 2017-19, we will begin a new project aiming to perform field trials in Merida, Mexico, evaluating the impact of metofluthrin passive emanators on Aedes aegypti biting behavior and abundance. 2017-2019.
As part of the "Partnership for Dengue Control" we have developed a framework to evaluate the epidemiological impact of vector control on dengue, after accounting for the role of human mobility in separating risk of infection from place of residence. The article, led by Bobby Reiner, shows how randomized control trials (the gold standard for intervention evaluation) can be adapted to account for human movement. Findings were published in PLoS Negl. Trop. Dis. 10(5): e0004588). On the right, we show how can we calculate time under treatment, a key variable modulating the impact of a vector control intervention.
In Mexico, we are evaluating the impact of two high-quality interventions: Indoor Residual Spraying and Insecticide Treated screens (i-Screens). We have published results of the positive entomologic impact of i-Screens on Aedes aegypti. This environmental management tool can have significant entomologic as well as quality of life impacts, which can trigger improvements in public health. Findings of our research were published by Manrique-Saide et al. Emerging Infectious Diseases, 21(2): 308-311, and Che-Mendoza et al. Transactions of the Royal Society of Tropical Medicine and Hygiene, 109: 106-115.)