Visit our publications page for a complete look at the work we've done in this research area.


Using an evidence-based approach, we conduct experimental and randomized field trials to evaluate the impact of existing and novel interventions on vector behavior and abundance or pathogen transmission. Such analyses depend on adequate surveillance platforms, and the Prokopec Lab has innovated in the development of better sampling methodologies, the incorporation of spatial analysis and mapping, and the evaluation of this enhanced surveillance in the context of urban mosquito control programs.


2018 - 2020

Innovative Vector Control Consortium (IVSS)

Targeted IRS for Aedes with Sumishield and Actellic 


The goal of this project is to evaluate the impact of novel residual insecticide formulations on pyrethroid-resistant Aedes aegypti by conducting entomological studies in experimental houses and field randomized controlled trials.

2020 - 2025

National Institute of Health

Quantifying the Epidemiological Impact of Targeted Indoor Residual Spraying on Aedes-Borne Diseases


The goal of this project is to conduct Phase III randomized controlled trials to evaluate the epidemiological impact of targeted indoor residual spraying, applied preventatively, on Aedes-borne diseases (dengue, Chikungunya, Zika)

2020 - 2022

Innovative Vector Control Consortium (IVSS)

An Implementation / Effectiveness Trial for the Community-Led Deployment of Spatial Emanators

The goal of this project is to conduct an entomological randomized controlled trial to evaluate the impact of deploying metofluthrin emanators as top-down, versus bottom-up, on Aedes aegypti indoor entomological indicators.

2020 - 2022

United States Agency for International Development (USAID)

Establishment of the Laboratory for the Development of Wolbachia-based Strategies for the Biological Control of Mosquito Aedes aegypti Vector of Dengue, Chikungunya, and Zika in the State of Yucatán

PI: Pablo-Manrique

The goal of this project is to build a factory for mass-rearing and release of Aedes aegypti mosquitoes transfected with WAlb-strain of Wolbachia

2016 - 2019

Centers for Disease Control and Prevention (CDC)

Enhanced Entomological Surveillance of Aedes aegypti in the Context of Dengue, Chikungunya, and Zika Transmission

CDC: OADS BAA 2016-N-17844

The goal of this project is to improve Aedes-borne virus surveillance by incorporating spatial analytics to passive surveillance data and by studying the sensitivity of indoor adult mosquito sampling to the detection of arbovirus infection.